Synthesis and in vitro evaluation of electrodeposited Barium titanate coating on Ti6Al4V

Shahram Rahmati, Mohammad Basir Basiriani, Mohammad Rafienia, Jaber Yaghini, Keyvan Raeissi



Osseointegration has been the concern of implantology for many years. Researchers have used various ceramic coatings for this purpose; however, piezoelectric ceramics (e.g., barium titanate [BTO]) are a novel fi eld of interest. In this regard, BTO (BaTiO3 , BTO) coating was fabricated by electrophoretic deposition on Ti6Al4V medical alloy, using sol-gel-synthesized nanometer BTO powder. Structure and morphologies were studied using X-ray diffraction and scanning electron microscopy (SEM), respectively. Bioactivity response of coated samples while immersion in simulated body fl uid (SBF) was evaluated by SEM and inductively coupled plasma (ICP) analysis. Cell compatibility was also studied via 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium assay and SEM imaging. Results showed homogenous coating with cubic structure and crystallite size of about 41 nm. SEM images indicated apatite formation on the coating after 7 days of SBF immersion, and ICP analysis approved ions concentration decrement in SBF. Cells showed fl attened morphology in intimate contact with coating after 7 days of culture. Altogether, coated samples demonstrated appropriate bioactivity and biocompatibility.


Barium titanate; Sol-gel; Electrophoretic deposition (EPD); Bioactivity; Cytotoxicity

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